Research Specialist C/D

Research Specialist C/D

University Overview

The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn's distinctive interdisciplinary approach to scholarship and learning. As an employer Penn has been ranked nationally on many occasions with the most recent award from Forbes who named Penn one of America's Best Employers By State in 2021.

Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play.

The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more.

Posted Job Title
Research Specialist C/D

Job Profile Title
Research Specialist C

Job Description Summary
A researcher with a knowledge in tumor immunology is sought to be involved in investigating the role of the inflammatory myeloid cells in the tumor microenvironment and the cellular and molecular mechanisms by which tumor modulates their immune functions in cancer patients and tumor-bearing mice. The research specialist is expected to participate in and perform experiments, data analysis and data presentation to investigate the role of the tumor-infiltrating inflammatory myeloid cells in the regulation of adaptive immunity in lung cancer patients. He/She will investigate the ability of tumor-associated neutrophils and macrophages to regulate tumor-specific T cell responses and to mediate antibody-dependent cell cytotoxicity. The potential candidate will also study the mechanisms underlying in anti-tumoral activity of newly discovered subset of APC-like tumor-associated neutrophils

Position is contingent upon funding.

Job Description

The Research Specialist C will be involved in all aspects of the individual projects. He/She is expected to conceive, participate in and perform experiments, data analysis, as well as independently manages the day-to-day operations of the lab in collaboration with Principal Investigator. Duties include performing flow cytometry, time lapse microscopy, cytotoxic assay, and working with mouse models (i.v, i.p, s.c injection, tissue harvesting). In addition to the aforementioned responsibilities will be involved in more complex experiments including evaluating tumoricidal activity of tumor-associated myeloid cells as well as they role in the regulation of T cell response in human lung tumors

The Research Specialist D will be responsible for developing and optimizing approaches and assays to investigate the effect of tumor-associated neutrophils and macrophages on anti-tumor T cell responses in lung cancer patients. In addition, He/She is expected to conceive, participate in and perform experiments evaluating the role of tumor -infiltrating myeloid cells in the regulation of immune response triggered by therapeutic anti-tumor antibodies. Position responsibilities include experiment design, performing experiments, data analysis and presentation. He/she must be able to perform and analyze the flow cytometry-based assays, cytokine multi-plex assay, basic assays of molecular biology. The Scientist will work independently to manage daily research projects, data collection and organization of the laboratory.

Position is contingent upon funding.

Research Specialist C: Bachelor's Degree with 3-5 years of related experience in research, clinical study, project and people management or equivalent combination of education and experience is required

Research Specialist D: The minimum of a Master's Degree and 3 years to 5 years of experience or equivalent combination of education and experience is required. Must have experience with research in the cellular and molecular aspects of tumor immunology. Should be highly organized and task oriented. Experience with performing flow cytometry-based assays is required.

Working Conditions
Office, Library, Computer Room; Requires extensive safety

Physical Effort
Typically sitting at a desk or table; Occasional lifting 25 lb. or less

Job Location - City, State
Philadelphia, Pennsylvania

Department / School
Perelman School of Medicine

Pay Range
$42,953.00 - $77,315.00

Affirmative Action Statement
Penn adheres to a policy that prohibits discrimination on the basis of race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status, or any other legally protected class.

Special Requirements
Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.

University Benefits
  • Health, Life, and Flexible Spending Accounts: Penn offers comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits to protect you and your family's health and welfare. You can also use flexible spending accounts to pay for eligible health care and dependent care expenses with pre-tax dollars.
  • Tuition: Take advantage of Penn's exceptional tuition benefits. You, your spouse, and your dependent children can get tuition assistance here at Penn. Your dependent children are also eligible for tuition assistance at other institutions.
  • Retirement: Penn offers generous retirement plans to help you save for your future. Penn's Basic, Matching, and Supplemental retirement plans allow you to save for retirement on a pre-tax or Roth basis. Choose from a wide variety of investment options through TIAA and Vanguard.
  • Time Away from Work: Penn provides you with a substantial amount of time away from work during the course of the year. This allows you to relax, take vacations, attend to personal affairs, recover from illness or injury, spend time with family-whatever your personal needs may be.
  • Long-Term Care Insurance: In partnership with Genworth Financial, Penn offers faculty and staff (and your eligible family members) long-term care insurance to help you cover some of the costs of long-term care services received at home, in the community or in a nursing facility. If you apply when you're newly hired, you won't have to provide proof of good health or be subject to underwriting requirements. Eligible family members must always provide proof of good health and are subject to underwriting.
  • Wellness and Work-life Resources: Penn is committed to supporting our faculty and staff as they balance the competing demands of work and personal life. That's why we offer a wide variety of programs and resources to help you care for your health, your family, and your work-life balance.
  • Professional and Personal Development: Penn provides an array of resources to help you advance yourself personally and professionally.
  • University Resources: As a member of the Penn community, you have access to a wide range of University resources as well as cultural and recreational activities. Take advantage of the University's libraries and athletic facilities, or visit our arboretum and art galleries. There's always something going on at Penn, whether it's a new exhibit at the Penn Museum, the latest music or theater presentation at the Annenberg Center, or the Penn Relays at Franklin Field to name just a few examples. As a member of the Penn community, you're right in the middle of the excitement-and you and your family can enjoy many of these activities for free.
  • Discounts and Special Services: From arts and entertainment to transportation and mortgages, you'll find great deals for University faculty and staff. Not only do Penn arts and cultural centers and museums offer free and discounted admission and memberships to faculty and staff. You can also enjoy substantial savings on other goods and services such as new cars from Ford and General Motors, cellular phone service plans, movie tickets, and admission to theme parks.
  • Flexible Work Hours: Flexible work options offer creative approaches for completing work while promoting balance between work and personal commitments. These approaches involve use of non-traditional work hours, locations, and/or job structures.
  • Penn Home Ownership Services: Penn offers a forgivable loan for eligible employees interested in buying a home or currently residing in West Philadelphia, which can be used for closing costs or home improvements.
  • Adoption Assistance: Penn will reimburse eligible employees on qualified expenses in connection with the legal adoption of an eligible child, such as travel or court fees, for up to two adoptions in your household.

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